Giuseppe Legname : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (133)
Les plus populaires
Liste
- Liste
- Tableau

1

Pharmacokinetics of quinacrine in the treatment of prion disease

Lotus Yung, Yong Huang, Pierre Lessard, Giuseppe Legname, Emil T Lin, Michael Baldwin, Stanley B Prusiner, Chongsuk Ryou, B Joseph Guglielmo

Journal:

BMC Infectious Diseases

Année:

2004

Langue:

english

Fichier:

PDF, 551 KB

english, 2004

2

A Change in the Conformation of Prions Accompanies the Emergence of a New Prion Strain

David Peretz, R.Anthony Williamson, Giuseppe Legname, Yoichi Matsunaga, Julie Vergara, Dennis R. Burton, Stephen J. DeArmond, Stanley B. Prusiner, Michael R. Scott

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 417 KB

english, 2002

3

The peculiar nature of unfolding of the human prion protein

Ilia V. Baskakov, Giuseppe Legname, Zygmunt Gryczynski, Stanley B. Prusiner

Journal:

Protein Science

Année:

2004

Langue:

english

Fichier:

PDF, 177 KB

english, 2004

4

Role of Prion Disease-Linked Mutations in the Intrinsically Disordered N-Terminal Domain of the Prion Protein

Cong, Xiaojing, Casiraghi, Nicola, Rossetti, Giulia, Mohanty, Sandipan, Giachin, Gabriele, Legname, Giuseppe, Carloni, Paolo

Journal:

Journal of Chemical Theory and Computation

Année:

2013

Langue:

english

Fichier:

PDF, 3.49 MB

english, 2013

5

Prion Protein-Specific Antibodies-Development, Modes of Action and Therapeutics Application

Rovis, Tihana, Legname, Giuseppe

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 679 KB

english, 2014

6

Cytosolic prion protein in neurons.

Mironov, Alexander, Latawiec, Diane, Wille, Holger, Bouzamondo-Bernstein, Essia, Legname, Giuseppe, Williamson, R Anthony, Burton, Dennis, DeArmond, Stephen J, Prusiner, Stanley B, Peters, Peter J

Journal:

The Journal of neuroscience : the official journal of the Society for Neuroscience

Année:

2003

Langue:

english

Fichier:

PDF, 861 KB

english, 2003

7

Genetic grafting of membrane-acting peptides to the cytotoxin dianthin augments its ability to de-stabilize lipid bilayers and enhances its cytotoxic potential as the component of transferrin-toxin conjugates

Irene Lorenzetti, Alessandra Meneguzzi, Giulio Fracasso, Cristina Potrich, Laura Costantini, Elena Chiesa, Giuseppe Legname, Gianfranco Menestrina, Giuseppe Tridente, Marco Colombatti

Journal:

International Journal of Cancer

Année:

2000

Langue:

english

Fichier:

PDF, 141 KB

english, 2000

8

ChemInform Abstract: Synthesis and Evaluation of a Library of 2,5-Bisdiamino-benzoquinone Derivatives as Probes to Modulate Protein—Protein Interactions in Prions.

Hoang Ngoc Ai Tran, Salvatore Bongarzone, Paolo Carloni, Giuseppe Legname, Maria Laura Bolognesi

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 27 KB

english, 2010

9

Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts

Salvatore Bongarzone, Hoang Ngoc Ai Tran, Prof. Andrea Cavalli, Prof. Marinella Roberti, Dr. Michela Rosini, Prof. Paolo Carloni, Prof. Giuseppe Legname, Prof. Maria Laura Bolognesi

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 257 KB

english, 2011

10

Neurodevelopmental expression and localization of the cellular prion protein in the central nervous system of the mouse

Stefano Benvegnù, Ilaria Poggiolini, Giuseppe Legname

Journal:

The Journal of Comparative Neurology

Année:

2010

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2010

11

Neurodevelopmental expression and localization of the cellular prion protein in the central nervous system of the mouse

Stefano Benvegnù, Ilaria Poggiolini, Giuseppe Legname

Journal:

The Journal of Comparative Neurology

Année:

2010

Fichier:

PDF, 323 KB

2010

12

Substrate recognition by ribosome-inactivating protein studied by molecular modeling and molecular electrostatic potentials

Gianpaolo Bravi, Giuseppe Legname, A.W.Edith Chan

Journal:

Journal of Molecular Graphics

Année:

1995

Langue:

english

Fichier:

PDF, 479 KB

english, 1995

13

Synthesis and evaluation of a library of 2,5-bisdiamino-benzoquinone derivatives as probes to modulate protein–protein interactions in prions

Hoang Ngoc Ai Tran, Salvatore Bongarzone, Paolo Carloni, Giuseppe Legname, Maria Laura Bolognesi

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 331 KB

english, 2010

14

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

Rose Zamoyska, Albert Basson, Andrew Filby, Giuseppe Legname, Matthew Lovatt, Benedict Seddon

Journal:

Immunological Reviews

Année:

2003

Langue:

english

Fichier:

PDF, 483 KB

english, 2003

15

A novel expression system for production of soluble prion proteins in E. coli

Romany NN Abskharon, Stephanie Ramboarina, Hassan El Hassan, Wael Gad, Marcin I Apostol, Gabriele Giachin, Giuseppe Legname, Jan Steyaert, Joris Messens, Sameh H Soror, Alexandre Wohlkonig

Journal:

Microbial Cell Factories

Année:

2012

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2012

16

Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells

Alessandro Didonna, Giuseppe Legname

Journal:

Molecular Neurodegeneration

Année:

2010

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2010

17

Structural facets of disease-linked human prion protein mutants: A molecular dynamic study

Giulia Rossetti, Gabriele Giachin, Giuseppe Legname, Paolo Carloni

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2010

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2010

18

Compact conformations of α-synuclein induced by alcohols and copper

Antonino Natalello, Federico Benetti, Silvia Maria Doglia, Giuseppe Legname, Rita Grandori

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2011

Langue:

english

Fichier:

PDF, 591 KB

english, 2011

19

Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro

Jamil Kanaani, Stanley B. Prusiner, Julia Diacovo, Steinunn Baekkeskov, Giuseppe Legname

Journal:

Journal of Neurochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2005

20

10.1038/35089090

Peretz, David, Williamson, R. Anthony, Kaneko, Kiotoshi, Vergara, Julie, Leclerc, Estelle, Schmitt-Ulms, Gerold, Mehlhorn, Ingrid R., Legname, Giuseppe, Wormald, Mark R., Rudd, Pauline M., Dwek, Raymo

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 291 KB

english, 2001

21

Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice

Safar, Jiri G., Scott, Michael, Monaghan, Jeff, Deering, Camille, Didorenko, Svetlana, Vergara, Julie, Ball, Haydn, Legname, Giuseppe, Leclerc, Estelle, Solforosi, Laura

Journal:

Nature Biotechnology

Année:

2002

Langue:

english

Fichier:

PDF, 579 KB

english, 2002

22

Differential Inhibition of Prion Propagation by Enantiomers of Quinacrine

Ryou, Chongsuk, Legname, Giuseppe, Peretz, David, Craig, John C, Baldwin, Michael A, Prusiner, Stanley B

Journal:

Laboratory Investigation

Année:

2003

Langue:

english

Fichier:

PDF, 700 KB

english, 2003

23

Identification and cloning of human chaperonin 10 homologue

Nicoletta Monzini, Giuseppe Legname, Fabrizio Marcucci, Gianni Gromo, Daniela Modena

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1994

Langue:

english

Fichier:

PDF, 566 KB

english, 1994

24

A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation

Gianpaolo Chiriano, Angela De Simone, Francesca Mancini, Daniel I. Perez, Andrea Cavalli, Maria Laura Bolognesi, Giuseppe Legname, Ana Martinez, Vincenza Andrisano, Paolo Carloni, Marinella Roberti

Journal:

European Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2012

25

Epitope mapping of a PrP(Sc)-specific monoclonal antibody: Identification of a novel C-terminally truncated prion fragment

Miha Kosmač, Simon Koren, Gabriele Giachin, Tatiana Stoilova, Renato Gennaro, Giuseppe Legname, Vladka Čurin Šerbec

Journal:

Molecular Immunology

Année:

2011

Langue:

english

Fichier:

PDF, 392 KB

english, 2011

26

Evidence for GroES Acting as a Transcriptional Regulator

Giuseppe Legname, Pasqualina Buono, Gianluca Fossati, Nicoletta Monzini, Paolo Mascagni, Daniela Modena, Fabrizio Marcucci

Journal:

Biochemical and Biophysical Research Communications

Année:

1996

Langue:

english

Fichier:

PDF, 152 KB

english, 1996

27

Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein

Gerold Schmitt-Ulms, Giuseppe Legname, Michael A Baldwin, Haydn L Ball, Nicole Bradon, Patrick J Bosque, Kathryn L Crossin, Gerald M Edelman, Stephen J DeArmond, Fred E Cohen, Stanley B Prusiner

Journal:

Journal of Molecular Biology

Année:

2001

Langue:

english

Fichier:

PDF, 493 KB

english, 2001

28

Single-chain ribosome inactivating proteins from plants depurinate Escherichia coli 23S ribosomal RNA

Martin R. Hartley, Giuseppe Legname, Rupert Osborn, Zhaochun Chen, J.Michael Lord

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 1.41 MB

english, 1991

29

Expression in Escherichia coli, purification and functional activity of recombinant human chaperonin 10

Giuseppe Legname, Gianluca Fossati, Gianni Gromo, Nicoletta Monzini, Fabrizio Marcucci, Daniela Modena

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 374 KB

english, 1995

30

Oxidation of methionine residues in the prion protein by hydrogen peroxide

Jesús R. Requena, Mariana N. Dimitrova, Giuseppe Legname, Susana Teijeira, Stanley B. Prusiner, Rodney L. Levine

Journal:

Archives of Biochemistry and Biophysics

Année:

2004

Langue:

english

Fichier:

PDF, 575 KB

english, 2004

31

Eosinophilic myocarditis in a patient with idiopathic hypereosinophilic syndrome: Insights into mechanisms of myocardial cell death

Domenico Corradi, Augusto Vaglio, Roberta Maestri, Vivian Legname, Giuseppe Leonardi, Giovanni Bartoloni, Carlo Buzio

Journal:

Human Pathology

Année:

2004

Langue:

english

Fichier:

PDF, 629 KB

english, 2004

32

Thioaptamer Interactions with Prion Proteins: Sequence-specific and Non-specific Binding Sites

David J. King, Jiri G. Safar, Giuseppe Legname, Stanley B. Prusiner

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 529 KB

english, 2007

33

Structural Insights into Alternate Aggregated Prion Protein Forms

Maurizio Polano, Alpan Bek, Federico Benetti, Marco Lazzarino, Giuseppe Legname

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2009

34

Common Structural Traits across Pathogenic Mutants of the Human Prion Protein and Their Implications for Familial Prion Diseases

Giulia Rossetti, Xiaojing Cong, Rocco Caliandro, Giuseppe Legname, Paolo Carloni

Journal:

Journal of Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2011

35

Toward the Molecular Basis of Inherited Prion Diseases: NMR Structure of the Human Prion Protein with V210I Mutation

Ivana Biljan, Gregor Ilc, Gabriele Giachin, Andrea Raspadori, Igor Zhukov, Janez Plavec, Giuseppe Legname

Journal:

Journal of Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2011

36

Corrigendum to “Common Structural Traits across Pathogenic Mutants of the Human Prion Protein and Their Implications for Familial Prion Diseases” [J. Mol. Biol. 411 (2011) 700–712]

Giulia Rossetti, Xiaojing Cong, Rocco Caliandro, Giuseppe Legname, Paolo Carloni

Journal:

Journal of Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 76 KB

english, 2012

37

Aged PrP null mice show defective processing of neuregulins in the peripheral nervous system

Stefano Benvegnù, Lisa Gasperini, Giuseppe Legname

Journal:

Molecular and Cellular Neuroscience

Année:

2011

Langue:

english

Fichier:

PDF, 828 KB

english, 2011

38

Conformation of PrPC on the Cell Surface as Probed by Antibodies

Estelle Leclerc, David Peretz, Haydn Ball, Laura Solforosi, Giuseppe Legname, Jiri Safar, Ana Serban, Stanley B. Prusiner, Dennis R. Burton, R.Anthony Williamson

Journal:

Journal of Molecular Biology

Année:

2003

Langue:

english

Fichier:

PDF, 435 KB

english, 2003

39

Cooperative Binding of Dominant-Negative Prion Protein to Kringle Domains

Chongsuk Ryou, Stanley B. Prusiner, Giuseppe Legname

Journal:

Journal of Molecular Biology

Année:

2003

Langue:

english

Fichier:

PDF, 630 KB

english, 2003

40

Mycobacterial Cpn10 promotes recognition of the mammalian homologue by a mycobacterium-specific antiserum

Manuela Minto, Grazia Galli, Elisabetta Gianazza, Ivano Eberini, Giuseppe Legname, Gianluca Fossati, Daniela Modena, Fabrizio Marcucci, Paolo Mascagni, Pietro Ghezzi, Maddalena Fratelli

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

1998

Langue:

english

Fichier:

PDF, 270 KB

english, 1998

41

Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP Thymocytes

Giuseppe Legname, Ben Seddon, Matthew Lovatt, Peter Tomlinson, Nitza Sarner, Mauro Tolaini, Keith Williams, Trisha Norton, Dimitris Kioussis, Rose Zamoyska

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 275 KB

english, 2000

42

S1-03-04: Transmission studies of mouse synthetic prions

Giuseppe Legname, Hoang-Oanh Bach Nguyen, Ilia V. Baskakov, Stephen J. DeArmond, Stanley B. Prusiner

Journal:

Alzheimer's & Dementia

Année:

2006

Langue:

english

Fichier:

PDF, 63 KB

english, 2006

43

Docking Ligands on Protein Surfaces: The Case Study of Prion Protein ‡

Kranjc, Agata, Bongarzone, Salvatore, Rossetti, Giulia, Biarnés, Xevi, Cavalli, Andrea, Bolognesi, Maria Laura, Roberti, Marinella, Legname, Giuseppe, Carloni, Paolo

Journal:

Journal of Chemical Theory and Computation

Année:

2009

Langue:

english

Fichier:

PDF, 370 KB

english, 2009

44

Structure−Activity Relationship Study of Prion Inhibition by 2-Aminopyridine-3,5-dicarbonitrile-Based Compounds: Parallel Synthesis, Bioactivity, and in Vitro Pharmacokinetics

May, Barnaby C. H., Zorn, Julie A., Witkop, Juanita, Sherrill, John, Wallace, Andrew C., Legname, Giuseppe, Prusiner, Stanley B., Cohen, Fred E.

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 228 KB

english, 2007

45

Gene expression profiling to identify druggable targets in prion diseases

Benetti, Federico, Gasperini, Lisa, Zampieri, Mattia, Legname, Giuseppe

Journal:

Expert Opinion on Drug Discovery

Année:

2010

Langue:

english

Fichier:

PDF, 388 KB

english, 2010

46

Functionalized gold nanoparticles: a detailed in vivo multimodal microscopic brain distribution study

Sousa, Fernanda, Mandal, Subhra, Garrovo, Chiara, Astolfo, Alberto, Bonifacio, Alois, Latawiec, Diane, Menk, Ralf Hendrik, Arfelli, Fulvia, Huewel, Sabine, Legname, Giuseppe, Galla, Hans-Joachim, Krol

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 362 KB

english, 2010

47

Humic substances interfere with detection of pathogenic prion protein

Smith, Christen B., Booth, Clarissa J., Wadzinski, Tyler J., Legname, Giuseppe, Chappell, Rick, Johnson, Christopher J., Pedersen, Joel A.

Journal:

Soil Biology and Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 876 KB

english, 2014

48

Oriented Prion Protein Immobilization at Nanostructured Interfaces

Sanavio, Barbara, Grunwald, Christian, Legname, Giuseppe, Scoles, Giacinto, Casalis, Loredana

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 55 KB

english, 2010

49

Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques

Barbisin, Maura, Vanni, Silvia, Schmädicke, Ann-Christin, Montag, Judith, Motzkus, Dirk, Opitz, Lennart, Salinas-Riester, Gabriela, Legname, Giuseppe

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 975 KB

english, 2014

50

Gene expression profiling and therapeutic interventions in neurodegenerative diseases: a comprehensive study on potentiality and limits

Benetti, Federico, Gustincich, Stefano, Legname, Giuseppe

Journal:

Expert Opinion on Drug Discovery

Année:

2012

Langue:

english

Fichier:

PDF, 281 KB

english, 2012